产品货号：
Z25435
中文名称：
RNASEH2A抗体
英文名称：
Anti-RNASEH2A Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RNASEH2A Antibody |
| 指标别名 | AGS4;JUNB;Ribonuclease H2 subunit A;ribonuclease H2;subunit A;Ribonuclease HI large subunit;Ribonuclease HI subunit A;RNase H(35);RNase H2 subunit A;RNase HI large subunit;RNASEH2A;RNASEHI;RNHIA;RNHL |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | RNASEH2A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | RNAse H2A antibody was raised against a 17 amino acid synthetic peptide near the center of human RNAse H2A.The immunogen is located within amino acids 190 - 240 of RNAse H2A. |
| 计算分子量 | 33kDa |
| 成分 | RNAse H2A Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | RNAse H2A Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids.The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair.RNAse H2 is made up of three subunits;all three are required for RNAse activity.Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS),a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid.Similar conditions are observed with mutations in TREX1,a single-stranded DNA exonuclease,suggesting that RNAse H2 and TREX1 may have similar roles,and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids,triggering an inflammatory response through activation of the innate immune system. |
| Uniprot ID | O75792 |
| 基因名全称 | Ribonuclease H2,subunit A |
| 蛋白名全称 | Ribonuclease H2,subunit A |
| 推荐稀释比 | RNAse H2A antibody can be used for detection of RNAse H2A by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 2μg/mL.For immunofluorescence start at 4μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索：RNASEH2A抗体，RNASEH2A多抗，Anti-RNASEH2A Antibody